Coronavirus in the elderly: a late lockdown UK cohort.
Identifieur interne : 002144 ( Main/Exploration ); précédent : 002143; suivant : 002145Coronavirus in the elderly: a late lockdown UK cohort.
Auteurs : Andrew D. Kerr ; Sybil Rl Stacpoole [Éthiopie]Source :
- Clinical medicine (London, England) [ 1473-4893 ] ; 2020.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen (MeSH), Betacoronavirus (MeSH), Comorbidité (MeSH), Femelle (MeSH), Humains (MeSH), Infections à coronavirus (diagnostic), Infections à coronavirus (mortalité), Infections à coronavirus (thérapie), Infections à coronavirus (épidémiologie), Mâle (MeSH), Pandémies (MeSH), Pneumopathie virale (diagnostic), Pneumopathie virale (mortalité), Pneumopathie virale (thérapie), Pneumopathie virale (épidémiologie), Royaume-Uni (épidémiologie), Résultat thérapeutique (MeSH), Sujet âgé (MeSH), Sujet âgé de 80 ans ou plus (MeSH), Études rétrospectives (MeSH).
- MESH :
- diagnostic : Infections à coronavirus, Pneumopathie virale.
- mortalité : Infections à coronavirus, Pneumopathie virale.
- thérapie : Infections à coronavirus, Pneumopathie virale.
- épidémiologie : Infections à coronavirus, Pneumopathie virale, Royaume-Uni.
- Adulte d'âge moyen, Betacoronavirus, Comorbidité, Femelle, Humains, Mâle, Pandémies, Résultat thérapeutique, Sujet âgé, Sujet âgé de 80 ans ou plus, Études rétrospectives.
- Wicri :
- geographic : Royaume-Uni.
English descriptors
- KwdEn :
- Aged (MeSH), Aged, 80 and over (MeSH), Betacoronavirus (MeSH), COVID-19 (MeSH), Comorbidity (MeSH), Coronavirus Infections (diagnosis), Coronavirus Infections (epidemiology), Coronavirus Infections (mortality), Coronavirus Infections (therapy), Female (MeSH), Humans (MeSH), Male (MeSH), Middle Aged (MeSH), Pandemics (MeSH), Pneumonia, Viral (diagnosis), Pneumonia, Viral (epidemiology), Pneumonia, Viral (mortality), Pneumonia, Viral (therapy), Retrospective Studies (MeSH), SARS-CoV-2 (MeSH), Treatment Outcome (MeSH), United Kingdom (epidemiology).
- MESH :
- geographic , epidemiology : United Kingdom.
- diagnosis : Coronavirus Infections, Pneumonia, Viral.
- epidemiology : Coronavirus Infections, Pneumonia, Viral.
- mortality : Coronavirus Infections, Pneumonia, Viral.
- therapy : Coronavirus Infections, Pneumonia, Viral.
- Aged, Aged, 80 and over, Betacoronavirus, COVID-19, Comorbidity, Female, Humans, Male, Middle Aged, Pandemics, Retrospective Studies, SARS-CoV-2, Treatment Outcome.
Abstract
OBJECTIVE
To identify the source of ongoing coronavirus disease 2019 (COVID-19) infections after 4 weeks of lockdown and to characterise the presentation of COVID-19 in the elderly, who represent the highest risk group.
DESIGN
Retrospective observational cohort study of 115 patients at one acute district general hospital with a catchment population of approximately 500,000 people, during weeks 5 and 6 of the UK lockdown.
RESULTS
More than 2 in 3 of the overall cohort had had contacts with the health and social care system prior to diagnosis. This figure rose to 85% in those 70 years and over. In the older cohort, the most common reasons for presentation were shortness of breath or falls, and 1 in 3 had neither cough nor fever.
CONCLUSION
COVID-19 can present differently in the elderly, overlapping with many common presentations, so focusing testing on those with a cough or fever will miss at least 1 in 3 cases in those over the age of 70. A high degree of vigilance, suspicion and repeated testing is required if streaming into high and low risk areas is to succeed, allowing safe restarting of services such as elective surgery and cancer care.
DOI: 10.7861/clinmed.2020-0423
PubMed: 32912964
PubMed Central: PMC7687331
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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Kerr</name><affiliation><nlm:affiliation>North West Anglia NHS Foundation Trust.</nlm:affiliation><wicri:noCountry code="no comma">North West Anglia NHS Foundation Trust.</wicri:noCountry></affiliation></author><author><name sortKey="Stacpoole, Sybil Rl" sort="Stacpoole, Sybil Rl" uniqKey="Stacpoole S" first="Sybil Rl" last="Stacpoole">Sybil Rl Stacpoole</name><affiliation wicri:level="1"><nlm:affiliation>North West Anglia NHS Foundation Trust sybilstacpoole@nhs.net.</nlm:affiliation><country wicri:rule="url">Éthiopie</country></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2020">2020</date><idno type="RBID">pubmed:32912964</idno><idno type="pmid">32912964</idno><idno type="doi">10.7861/clinmed.2020-0423</idno><idno type="pmc">PMC7687331</idno><idno type="wicri:Area/Main/Corpus">001760</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">001760</idno><idno type="wicri:Area/Main/Curation">001760</idno><idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">001760</idno><idno type="wicri:Area/Main/Exploration">001760</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Coronavirus in the elderly: a late lockdown UK cohort.</title><author><name sortKey="Kerr, Andrew D" sort="Kerr, Andrew D" uniqKey="Kerr A" first="Andrew D" last="Kerr">Andrew D. Kerr</name><affiliation><nlm:affiliation>North West Anglia NHS Foundation Trust.</nlm:affiliation><wicri:noCountry code="no comma">North West Anglia NHS Foundation Trust.</wicri:noCountry></affiliation></author><author><name sortKey="Stacpoole, Sybil Rl" sort="Stacpoole, Sybil Rl" uniqKey="Stacpoole S" first="Sybil Rl" last="Stacpoole">Sybil Rl Stacpoole</name><affiliation wicri:level="1"><nlm:affiliation>North West Anglia NHS Foundation Trust sybilstacpoole@nhs.net.</nlm:affiliation><country wicri:rule="url">Éthiopie</country></affiliation></author></analytic><series><title level="j">Clinical medicine (London, England)</title><idno type="eISSN">1473-4893</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged (MeSH)</term><term>Aged, 80 and over (MeSH)</term><term>Betacoronavirus (MeSH)</term><term>COVID-19 (MeSH)</term><term>Comorbidity (MeSH)</term><term>Coronavirus Infections (diagnosis)</term><term>Coronavirus Infections (epidemiology)</term><term>Coronavirus Infections (mortality)</term><term>Coronavirus Infections (therapy)</term><term>Female (MeSH)</term><term>Humans (MeSH)</term><term>Male (MeSH)</term><term>Middle Aged (MeSH)</term><term>Pandemics (MeSH)</term><term>Pneumonia, Viral (diagnosis)</term><term>Pneumonia, Viral (epidemiology)</term><term>Pneumonia, Viral (mortality)</term><term>Pneumonia, Viral (therapy)</term><term>Retrospective Studies (MeSH)</term><term>SARS-CoV-2 (MeSH)</term><term>Treatment Outcome (MeSH)</term><term>United Kingdom (epidemiology)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen (MeSH)</term><term>Betacoronavirus (MeSH)</term><term>Comorbidité (MeSH)</term><term>Femelle (MeSH)</term><term>Humains (MeSH)</term><term>Infections à coronavirus (diagnostic)</term><term>Infections à coronavirus (mortalité)</term><term>Infections à coronavirus (thérapie)</term><term>Infections à coronavirus (épidémiologie)</term><term>Mâle (MeSH)</term><term>Pandémies (MeSH)</term><term>Pneumopathie virale (diagnostic)</term><term>Pneumopathie virale (mortalité)</term><term>Pneumopathie virale (thérapie)</term><term>Pneumopathie virale (épidémiologie)</term><term>Royaume-Uni (épidémiologie)</term><term>Résultat thérapeutique (MeSH)</term><term>Sujet âgé (MeSH)</term><term>Sujet âgé de 80 ans ou plus (MeSH)</term><term>Études rétrospectives (MeSH)</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>United Kingdom</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Infections à coronavirus</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="mortality" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="mortalité" xml:lang="fr"><term>Infections à coronavirus</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="thérapie" xml:lang="fr"><term>Infections à coronavirus</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Infections à coronavirus</term><term>Pneumopathie virale</term><term>Royaume-Uni</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Betacoronavirus</term><term>COVID-19</term><term>Comorbidity</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Pandemics</term><term>Retrospective Studies</term><term>SARS-CoV-2</term><term>Treatment Outcome</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Betacoronavirus</term><term>Comorbidité</term><term>Femelle</term><term>Humains</term><term>Mâle</term><term>Pandémies</term><term>Résultat thérapeutique</term><term>Sujet âgé</term><term>Sujet âgé de 80 ans ou plus</term><term>Études rétrospectives</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Royaume-Uni</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>OBJECTIVE</b></p><p>To identify the source of ongoing coronavirus disease 2019 (COVID-19) infections after 4 weeks of lockdown and to characterise the presentation of COVID-19 in the elderly, who represent the highest risk group.</p></div><div type="abstract" xml:lang="en"><p><b>DESIGN</b></p><p>Retrospective observational cohort study of 115 patients at one acute district general hospital with a catchment population of approximately 500,000 people, during weeks 5 and 6 of the UK lockdown.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>More than 2 in 3 of the overall cohort had had contacts with the health and social care system prior to diagnosis. This figure rose to 85% in those 70 years and over. In the older cohort, the most common reasons for presentation were shortness of breath or falls, and 1 in 3 had neither cough nor fever.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSION</b></p><p>COVID-19 can present differently in the elderly, overlapping with many common presentations, so focusing testing on those with a cough or fever will miss at least 1 in 3 cases in those over the age of 70. A high degree of vigilance, suspicion and repeated testing is required if streaming into high and low risk areas is to succeed, allowing safe restarting of services such as elective surgery and cancer care.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">32912964</PMID><DateCompleted><Year>2020</Year><Month>11</Month><Day>30</Day></DateCompleted><DateRevised><Year>2020</Year><Month>12</Month><Day>18</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1473-4893</ISSN><JournalIssue CitedMedium="Internet"><Volume>20</Volume><Issue>6</Issue><PubDate><Year>2020</Year><Month>11</Month></PubDate></JournalIssue><Title>Clinical medicine (London, England)</Title><ISOAbbreviation>Clin Med (Lond)</ISOAbbreviation></Journal><ArticleTitle>Coronavirus in the elderly: a late lockdown UK cohort.</ArticleTitle><Pagination><MedlinePgn>e222-e228</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.7861/clinmed.2020-0423</ELocationID><Abstract><AbstractText Label="OBJECTIVE">To identify the source of ongoing coronavirus disease 2019 (COVID-19) infections after 4 weeks of lockdown and to characterise the presentation of COVID-19 in the elderly, who represent the highest risk group.</AbstractText><AbstractText Label="DESIGN">Retrospective observational cohort study of 115 patients at one acute district general hospital with a catchment population of approximately 500,000 people, during weeks 5 and 6 of the UK lockdown.</AbstractText><AbstractText Label="RESULTS">More than 2 in 3 of the overall cohort had had contacts with the health and social care system prior to diagnosis. This figure rose to 85% in those 70 years and over. In the older cohort, the most common reasons for presentation were shortness of breath or falls, and 1 in 3 had neither cough nor fever.</AbstractText><AbstractText Label="CONCLUSION">COVID-19 can present differently in the elderly, overlapping with many common presentations, so focusing testing on those with a cough or fever will miss at least 1 in 3 cases in those over the age of 70. A high degree of vigilance, suspicion and repeated testing is required if streaming into high and low risk areas is to succeed, allowing safe restarting of services such as elective surgery and cancer care.</AbstractText><CopyrightInformation>© 2020 Royal College of Physicians 2020. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Kerr</LastName><ForeName>Andrew D</ForeName><Initials>AD</Initials><AffiliationInfo><Affiliation>North West Anglia NHS Foundation Trust.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Stacpoole</LastName><ForeName>Sybil Rl</ForeName><Initials>SR</Initials><AffiliationInfo><Affiliation>North West Anglia NHS Foundation Trust sybilstacpoole@nhs.net.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D064888">Observational Study</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>09</Month><Day>10</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Clin Med 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Kerr</name></noCountry><country name="Éthiopie"><noRegion><name sortKey="Stacpoole, Sybil Rl" sort="Stacpoole, Sybil Rl" uniqKey="Stacpoole S" first="Sybil Rl" last="Stacpoole">Sybil Rl Stacpoole</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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